TABLE 3.

Summary of 6 cases with similar histologic features in the endometrial and endocervical tumors

Patient no.	FIGO stage	FIGO grade	Size and location of tumor in the endometrium	Myometrial invasion/full thickness of uterine wall (mm)	Size/location of tumor in the endocervix	Endocervical stromal invasion/full thickness of cervical wall (mm)	Histologic features	Studies performed
9	IIa	2	Diffusely thickened endometrium of 17 mm	12/28	No tumor identified on gross exam	N/A	Endometrioid	Clonality
10	IIb (synchronous right ovarian tumor)	2	5 × 5 mm posterior lower uterine segment	1/18	Extending to upper endocervix	1-mm deep (no full thickness of cervical wall)	Endometrioid with papillary features	Immunohistochemistry
11	III	2	Necrotic endometrium	> 50%	Extending to the entire cervix	Involving both mucosa and stroma	Endometrioid	Immunohistochemistry, HPV DNA/RNA analyses, and clonality
12	IIb	2	20-mm lower uterine segment	2/17	Grossly no tumor present in the cone biopsy specimen or hysterectomy specimen	3.2 mm deep in the cone biopsy specimen	Endometrioid with extensive papillary areas	Immunohistochemistry and clonality
13	IIb	2	40-mm cystic structure and 15-mm solid area, 1 cm apart, in the lower uterine segment	2/20	No tumor identified on gross exam	14/20	Endometrioid	Immunohistochemistry, HPV DNA/RNA in situ analyses, and clonality
14*	IIb	1	N/A	N/A	N/A	30/30	Endometrioid	Immunohistochemistry, HPV DNA/RNA analyses, and clonality

^*Endometrial biopsy and cervical biopsy specimen only.

HPV indicates human papillomavirus; N/A indicates not available.