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. 2020 Jul 24;13:7137–7149. doi: 10.2147/OTT.S254735

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© 2020 Wang et al.

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MiR-129-5p inhibits the growth and metastasis of LCCs by targeting HMGB1. (A) Relative expression of si-HMGB1 in constructed vectors according to the RT-qPCR assay. (B) Relative mRNA and protein expression of HMGB1 in transfected LCCs according to the RT-qPCR and WB assays. (C) Changes in the proliferation of LCCs after transfection of si-HMGB1 and si-HMGB1+miR-129-5p-inhibit according to the CCK-8 assay. (D) Transmembrane rate of LCCs transfected with si-HMGB1 and si-HMGB1+miR-129-5p-inhibit according to the CCK-8 assay. (E) Apoptosis induction of LCCs after transfection of si-HMGB1 and si-HMGB1+miR-129-5p-inhibit according to the flow cytometry. *indicates P<0.05.