Table 4.
The AUC of Th17 Cell-Related Cytokine CSF Levels in 108 Patients
| AUC | Cutoff | Se (%) | Sp (%) | |
|---|---|---|---|---|
| IL-10 (pg/mL) | 0.83 | 8.3 | 59 | 98 |
| IL-6 (pg/mL) | 0.50 | 4.2 | 30 | 67 |
| IL-10/IL-6 | 0.84 | 1.6 | 66 | 91 |
| IL-4 (pg/mL) | 0.62 | 8.8 | 30 | 79 |
| IL-17A (pg/mL) | 0.58 | 4.7 | 67 | 81 |
| IL-22 (pg/mL) | 0.57 | 13.6 | 53 | 52 |
| sCD40L (pg/mL) | 0.55 | 13.3 | 46 | 55 |
| TNF-α (pg/mL) | 0.58 | 1.9 | 37 | 79 |
| CSF protein (mg/l) | 0.55 | 0.63 | 31 | 63 |
| CSF WBC (x106/l) | 0.43 | 24 | 12 | 87 |
| Serum LDH (U/l) | 0.50 | 185 | 45 | 55 |
| Serum β2-MG (mg/l) | 0.41 | 1.65 | 39 | 50 |
| CLR (%) | 0.63 | 78 | 73 | 50 |
| CMR (%) | 0.72 | 4.5 | 48 | 76 |
Abbreviations: CLR, CSF mature lymphocyte ratio; CMR, CSF monocyte/macrophage ratio; AUC, area under the curve; Se, sensitivity; Sp, specificity.