Table 1.
Verrucous pilar and hybrid pilar-epidermoid cysts
| Case | Cyst Type | Age | Sex | Location | Initial Diagnosis | Clinical Impression | PCR | IHC |
|---|---|---|---|---|---|---|---|---|
| 1 | Hybrid | 57 | Female | Left mid back | Combined epidermoid and verrucous cyst | r/o BCC vs. EIC | - | β-HPV E4 |
| 2 | Pilar | 30 | Male | Left upper forehead | Verrucous cyst | r/o cyst | - | - |
| 3 | Pilar | 52 | Male | Left distal pretibial region | Verrucous cyst | NUB vs. DN vs. DF | - | - |
| 4 | Pilar | 52 | Male | Right lateral back | Combined pilar and verrucous cyst | Inflammatory papule r/o cyst | HPV-24 | β-HPV E4 |
| 5 | Pilar | 70 | Female | Posterior scalp | Verrucous cyst | NUB vs. BCC | - | - |
| 6 | Hybrid | 62 | Female | Right preauricular area | Hybrid epidermoid and pilar cyst | r/o EIC | HPV-24 | β-HPV E4 |
| 7 | Pilar | 57 | Male | Right under arm | Ruptured combined pilar and verrucous cyst with granulomatous dermatitis | Sebaceous cyst | - | - |
| 8 | Pilar | 66 | Male | Left mid back | Verrucous cyst Superimposed prurigo changes The lesion extends to the deep margin |
r/o ISK | - | - |
| 9 | Pilar | 57 | Female | Right thigh | Verrucous cyst, ruptured | EIC vs. DF vs. DFSP vs. MCC vs. other | - | - |
| 10 | Pilar | 19 | Female | Right distal pretibial region | Verrucous cyst | NUB vs. cyst | - | - |
Abbreviations: BCC, basal cell carcinoma; DF, dermatofibroma; DFSP, dermatofibrosarcoma protuberans; DN, dysplastic nevus; EIC, epidermal inclusion cyst; HPV, human papillomavirus; IHC, immunohistochemistry; ISK, inflamed seborrheic keratosis; MCC, Merkel cell carcinoma; NUB, neoplasm of uncertain behavior; PCR, polymerase chain reaction.