Ma 2015.
| Methods |
Type of trial: efficacy trial Allocation: randomised Intervention model: parallel assignment Masking: — Primary purpose: — |
| Participants |
Condition: T2DM Enrollment: 90 participants Inclusion criteria: — Exclusion criteria: — |
| Interventions |
Intervention(s): metformin (1500 mg/day) Comparator(s): pioglitazone (15 mg/day) |
| Outcomes |
Primary outcome(s): — Secondary outcome(s): — Other outcome(s): blood levels of glucose, insulin and glucagon, insulin sensitivity index, HOMA‐IR, HOMA‐β, 1‐phase index, 2‐phase index, insulin secretion sensitivity index |
| Study details | Trial identifier: — |
| Publication details |
Language of publication: Chinese / English (abstract) Funding: — Publicationstatus: full article / peer‐reviewed journal |
| Stated aim of study | Quote from publication: "To observe and evaluate the effects of metformin and pioglitazone on blood glucose, insulin, glucagon, β‐cell function and insulin resistance among patients with diabetes and metabolic syndrome, so as to discuss the role of pancreatic a cells in pathogenesis of type 2 diabetes mainly caused by insulin resistance and the change of a‐cell function after treatment." |
| Notes | Marked as a study awaiting classification due to publication being in Chinese and a lack of data to assess inclusion. Translators have been contacted. Trial author have been contacted |