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. 2020 Jun 5;2020(6):CD012906. doi: 10.1002/14651858.CD012906.pub2

Ma 2015.

Methods Type of trial: efficacy trial
Allocation: randomised
Intervention model: parallel assignment
Masking: —
Primary purpose: —
Participants Condition: T2DM
Enrollment: 90 participants
Inclusion criteria: —
Exclusion criteria: —
Interventions Intervention(s): metformin (1500 mg/day)
Comparator(s): pioglitazone (15 mg/day)
Outcomes Primary outcome(s): —
Secondary outcome(s): —
Other outcome(s): blood levels of glucose, insulin and glucagon, insulin sensitivity index, HOMA‐IR, HOMA‐β, 1‐phase index, 2‐phase index, insulin secretion sensitivity index
Study details Trial identifier: —
Publication details Language of publication: Chinese / English (abstract)
Funding: —
Publicationstatus: full article / peer‐reviewed journal
Stated aim of study Quote from publication: "To observe and evaluate the effects of metformin and pioglitazone on blood glucose, insulin, glucagon, β‐cell function and insulin resistance among patients with diabetes and metabolic syndrome, so as to discuss the role of pancreatic a cells in pathogenesis of type 2 diabetes mainly caused by insulin resistance and the change of a‐cell function after treatment."
Notes Marked as a study awaiting classification due to publication being in Chinese and a lack of data to assess inclusion. Translators have been contacted. Trial author have been contacted