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. 2020 Jul 28;9:e56177. doi: 10.7554/eLife.56177

Figure 3. Gonadectomy affects weight and body composition, and rescues a male-specific effect of hepatic Rictor deletion on fat mass.

Figure 3.

(A, B) The weight of A) male and (B) female mice lacking hepatic Rictor (L-RKO) and their wild-type (WT) littermates was tracked starting at 3 months of age (n varies by month; maximum female N = 22–26 mice/group, maximum male N = 20–23 mice/group). (C–F) The lean mass (C, D) and fat mass (E, F) of mice was determined every 4 months starting at 8 months of age (n varies by month; max female N = 9–17/group; max male N = 12–17/group). p-values for the overall effect of genotype (GT) or surgical treatment (Surgery) represent the p-value from pairwise two-way ANOVA testing. Error bars represent SEM.