Skip to main content
. Author manuscript; available in PMC: 2020 Jul 28.
Published in final edited form as: Brain Behav Immun. 2017 Aug 30;67:181–193. doi: 10.1016/j.bbi.2017.08.021

Figure 9. Circadian timing influences efficacy of (+)-Naltrexone on decreasing the mRNA expression of the TLR4-signaling pathway.

Figure 9

There was a significant effect of pretreatment on the expression of Tlr4 and Ifnb in the nucleus accumbens and Ifnb in the hypothalamus. Post hoc analyses determined differences between the groups were observed in the dark cycle only. All data was analysed using a two-way ANOVA with Bonferonni post hoc. Summary values represented as mean±SEM; n=3, *p < 0.05, **p < 0.01.