Skip to main content
. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Bone. 2020 May 16;137:115434. doi: 10.1016/j.bone.2020.115434

Table 3.

Summary of microRNAs related to growth plate development.

Name Functional site Phenotype of each KO mice Target genes Reference
miRNA-140 Proliferating zone Hyposkeletal formation, Inhibition of chondrocyte proliferation Negative regulation of Dnpep, Rala and HDAC4 [168–171]
miRNA-322 Pre-hypertrophic zone to hypertrophic zone Slight reduction of hepertrophic zone Unknown [176]
miRNA-21 Proliferating zone? In Gas5 overexpressing mice, Gas 5 suppress miRNA-21 and suppression of cell proliferation Unknown [181]