Nazarpour 2007.
Methods | RCT, parallel‐group | |
Participants | Included: students with moderate to severe primary dysmenorrhoea Excluded: underlying disease (which leads to dysmenorrhoea Secondary cause, such as endometriosis, myoma, ovarian tumours). And contraindications to the use of drugs. Age: mean 20.7 years Source: student population Location: Iran |
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Interventions | Group 1: fennel (N = 36) Group 2: mefenamic acid (N = 36) Group 3: placebo (N = 32) Dosing regimen: 2 cycles Total daily dose: fennel 20 to 30 drops every 4 to 8 hours (according to need) Mefenamic acid: 250 mg every 6 hours (100 mg/day) |
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Outcomes |
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Notes | Translated from Persian | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: the study authors did not report the method of sequence generation. |
Allocation concealment (selection bias) | Unclear risk | Comment: the study authors did not report the method of allocation concealment. |
Blinding (performance bias and detection bias) All outcomes | Low risk | Comment: both the clinician and participants were blinded. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Comment: the study authors included 104/120 participants (86%) in the analyses. |
Selective reporting (reporting bias) | Unclear risk | Comment: does not systematically report adverse events. |
Other bias | Low risk | Comment: we did not identify any other potential sources of bias. |