IRCT2014040117111N1.

Trial name or title	Comparison of the influence Nigella sativa with mefenamic acid on primary dysmenorrhoea
Methods	RCT
Participants	Inclusion criteria: age range between 18 to 30 years, single, female students staying in Iran Mashhad University dormitories, with regular menstrual periods of moderate to severe primary dysmenorrhoea grade based on a visual scale Exclusion criteria: history abdominal or pelvic surgery, history of sexual problems or mishaps during study, coagulation disorders or abnormal uterine pelvic ultrasound, consumption of hormonal drugs (e.g. contraception), NSAIDs, opioids, or any sensitivity to drugs, obesity (BMI > 30) Location: Iran
Interventions	Group 1: oral Nigella sativa 3 g daily (two capsules of 500 mg every 8 hours) during the first 3 days of menstruation Group 2: mefenamic acid 250 mg (two 500 mg capsules with 125 mg of active ingredient mefenamic acid every 8 hours during the first 3 days of menstruation
Outcomes	Intensity and duration of menstrual pain. Timepoint: 2 cycles before the intervention, and the first and second cycles of the intervention. Method of measurement: VAS and the scale Cox.
Starting date	01 November 2014
Contact information	Farzaneh Jafaarnejad (jaafarnejadf@mums.ac.ir)
Notes