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. 2012 Aug 15;2012(8):CD007566. doi: 10.1002/14651858.CD007566.pub2

Comparison 11. Physical functioning.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
11.1 Overall physical functioning change 11   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
11.1.1 Up to 12 weeks' follow‐up 5 386 Std. Mean Difference (IV, Random, 95% CI) 0.29 [‐0.08, 0.66]
11.1.2 More than 12 weeks' less than 6 months' follow‐up 3 246 Std. Mean Difference (IV, Random, 95% CI) 0.28 [‐0.28, 0.85]
11.1.3 6 months' follow‐up 3 189 Std. Mean Difference (IV, Random, 95% CI) ‐0.11 [‐0.69, 0.48]
11.1.4 More than 6 months' follow‐up 1 120 Std. Mean Difference (IV, Random, 95% CI) 0.14 [‐0.21, 0.50]
11.2 Overall physical functioning follow‐up values 20   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
11.2.1 Up to 12 weeks' follow‐up 15 878 Std. Mean Difference (IV, Random, 95% CI) 0.36 [0.09, 0.64]
11.2.2 More than 12 weeks' less than 6 months' follow‐up 7 559 Std. Mean Difference (IV, Random, 95% CI) 0.25 [‐0.05, 0.54]
11.2.3 6 months' follow‐up 2 110 Std. Mean Difference (IV, Random, 95% CI) 0.19 [‐0.18, 0.57]
11.2.4 More than 6 months' follow‐up 1 120 Std. Mean Difference (IV, Random, 95% CI) 0.19 [‐0.17, 0.55]
11.3 FACT physical function subscale change 6   Mean Difference (IV, Random, 95% CI) Subtotals only
11.3.1 Up to 12 weeks' follow‐up 3 313 Mean Difference (IV, Random, 95% CI) 0.74 [‐1.14, 2.62]
11.3.2 More than 12 weeks' less than 6 months' follow‐up 2 145 Mean Difference (IV, Random, 95% CI) 1.22 [‐0.97, 3.41]
11.3.3 6 months' follow‐up 2 110 Mean Difference (IV, Random, 95% CI) 0.64 [‐0.60, 1.89]
11.4 FACT physical function subscale follow‐up values 9 673 Mean Difference (IV, Random, 95% CI) 1.13 [‐0.09, 2.35]
11.4.1 Up to 12 weeks' follow‐up 6 356 Mean Difference (IV, Random, 95% CI) 1.60 [‐0.71, 3.92]
11.4.2 More than 12 weeks' less than 6 months' follow‐up 3 207 Mean Difference (IV, Random, 95% CI) 0.55 [‐0.45, 1.55]
11.4.3 6 months' follow‐up 2 110 Mean Difference (IV, Random, 95% CI) 0.85 [‐0.58, 2.28]
11.5 QLQ‐C30 subscale change 3   Mean Difference (IV, Random, 95% CI) Subtotals only
11.5.1 More than 12 weeks' less than 6 months' follow‐up 2 73 Mean Difference (IV, Random, 95% CI) 6.23 [1.74, 10.72]
11.5.2 More than 12 weeks' less than 6 months' follow‐up 1 101 Mean Difference (IV, Random, 95% CI) 0.30 [‐6.83, 7.43]
11.6 QLQ‐C30 subscale follow‐up values 5   Mean Difference (IV, Random, 95% CI) Subtotals only
11.6.1 Up to 12 weeks' follow‐up 4 256 Mean Difference (IV, Random, 95% CI) 2.55 [‐0.29, 5.38]
11.6.2 More than 12 weeks' less than 6 months' follow‐up 2 206 Mean Difference (IV, Random, 95% CI) 0.90 [‐6.83, 8.64]
11.7 MOS SF‐36 subscale change 3   Mean Difference (IV, Random, 95% CI) Subtotals only
11.7.1 Up to 12 weeks' follow‐up 1 58 Mean Difference (IV, Random, 95% CI) 6.11 [‐1.19, 13.41]
11.7.2 6 months' follow‐up 1 74 Mean Difference (IV, Random, 95% CI) ‐0.20 [‐2.37, 1.97]
11.7.3 More than 6 months' follow‐up 1 120 Mean Difference (IV, Random, 95% CI) 2.50 [‐3.66, 8.66]
11.8 MOS SF‐12 subscale follow‐up values 3   Mean Difference (IV, Random, 95% CI) Subtotals only
11.8.1 Up to 12 weeks' follow‐up 3 172 Mean Difference (IV, Random, 95% CI) 4.74 [0.31, 9.17]
11.8.2 More than 12 weeks' less than 6 months' follow‐up 1 87 Mean Difference (IV, Random, 95% CI) 2.12 [‐2.18, 6.42]
11.9 MOS SF‐36 subscale follow‐up values 3 323 Mean Difference (IV, Random, 95% CI) 6.42 [1.14, 11.71]
11.9.1 Up to 12 weeks' follow‐up 1 59 Mean Difference (IV, Random, 95% CI) 9.83 [5.26, 14.40]
11.9.2 6 months' follow‐up 2 144 Mean Difference (IV, Random, 95% CI) 7.93 [‐4.16, 20.02]
11.9.3 More than 6 months' follow‐up 1 120 Mean Difference (IV, Random, 95% CI) 1.40 [‐1.25, 4.05]
11.10 CARES subscale change 1 79 Mean Difference (IV, Random, 95% CI) ‐3.30 [‐5.54, ‐1.06]
11.10.1 6 months' follow‐up 1 79 Mean Difference (IV, Random, 95% CI) ‐3.30 [‐5.54, ‐1.06]
11.11 CARES subscale follow‐up values 1   Mean Difference (IV, Random, 95% CI) Subtotals only
11.11.1 6 months' follow‐up 1 79 Mean Difference (IV, Random, 95% CI) ‐4.10 [‐7.06, ‐1.14]
11.12 Body Esteem Scale ‐ physical condition follow‐up values 2   Mean Difference (IV, Random, 95% CI) Subtotals only
11.12.1 Up to 12 weeks' follow‐up 2 106 Mean Difference (IV, Random, 95% CI) 4.41 [0.57, 8.25]