Bai 2004.

Study characteristics
Methods	Study design: RCT Number randomized: 45; 24 to the exercise group and 21 to the control group Study start, 2003; stop date, not reported Length of intervention: 3 months Length of follow‐up: to end of the intervention
Participants	Type cancer: nasopharyngeal carcinoma Time since cancer diagnosis: unclear Time beyond active treatment: immediately after radiation therapy Inclusion criteria: treated using same method and dosage of radiation therapy KPS score > 60 Eligibility criterion related to interest or ability to exercise, or both: none reported Exclusion criteria: transfer to distant location chronic disease treated using chemotherapy distant metastasis Gender, n: male, 26, female, 19 Current age: 23 to 65 years old Age at cancer diagnosis: not reported Ethnicity/race: 100% Asian Education level: not reported SES: not reported Employment status: not reported Comorbidities: not reported Past exercise history: not reported
Interventions	24 participants assigned to the exercise intervention, including: exercise of low to medium strength including jogging, swimming, and exercise with equipment every day relaxation training of body muscles at least once per day education on the diseases and psychological support Type exercise (aerobic/anaerobic): aerobic and anaerobic Intensity of experimental exercise intervention: low to moderate Frequency: once a day Duration of individual sessions: not reported Duration of exercise program: 3 months Total number of exercise sessions: unclear Participants were monitored every 2 weeks Format: individual Facility: not reported Professionally led: not reported Adherence: not reported Control group: 21 participants assigned to control group, including no exercise Contamination of control group: none
Outcomes	Outcomes: QoL and physiologic outcomes, including: QoL, assessed using the EORTC QLQ‐C30; subscales included physical well‐being, role function, EWB, social function, and cognitive function nausea and vomiting fatigue, but unclear how assessed pain, but unclear how assessed Outcomes were measured at baseline and at 3 months: exercise group: n = 24 at baseline, n = 24 after the intervention control group: n = 21 at baseline, n = 21 after intervention Adverse events: none reported
Notes	Country: China Funding: not reported Correspondence with investigator sought
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	The generation of the random sequence was not described
Allocation concealment (selection bias)	Unclear risk	Whether the treatment assignment was concealed from study personnel and participants was not described
Blinding of participants and personnel (performance bias) All outcomes	High risk	Owing to the nature of the intervention, it was not possible to blind the participants; however, it is unclear whether the outcome was influenced by a lack of masking
Blinding of outcome assessment (detection bias) All outcomes	High risk	Study personnel and outcome assessors were not masked or blinded to the study interventions
Incomplete outcome data (attrition bias) All outcomes	Low risk	No study participants were lost to follow‐up and all were included in the analyses
Selective reporting (reporting bias)	Low risk	There appears to be no selective reporting of outcomes
Other bias	Low risk	The trial appears to be free of other problems that could put it at a high risk of bias