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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: J Pediatr. 2020 Jun 9;223:141–147.e4. doi: 10.1016/j.jpeds.2020.04.039

Table 3.

Frequency and cumulative dose for inhaled and intravenous anesthesia agents

Patients receiving agent Cumulative Exposure per Patient
n % Mean SD Median Min Max
Inhaled Agents Sevoflurane 92 91.09 1.83 1.27 2.00 0.00 6.00
Nitrus Oxide 47 46.53 0.62 0.85 0.00 0.00 4.00
Isoflurane 15 14.85 0.18 0.48 0.00 0.00 3.00
Desflurane 5 4.95 0.05 0.22 0.00 0.00 1.00
Halothane 1 0.99 0.01 0.10 0.00 0.00 1.00
Patients receiving agent Cumulative Dose per Patient
Intravenous Agents Propofol (mg/kg) 101 100 6169.92 5345.35 4055.00 150.00 24846.00
Fentanyl (mcg/kg) 101 100 327.11 297.28 200.00 50.00 1465.00
Midazolam (mg/kg) 61 60.4 5.87 11.37 1.00 0.00 70.00
Morphine (mg/kg) 27 26.73 2.95 11.64 0.00 0.00 85.00
Pentobarbitol (mg/kg) 18 17.82 53.32 141.56 0.00 0.00 910.00
Meperidine (mg/kg) 13 12.87 13.58 48.16 0.00 0.00 380.00
Ketamine (mg/kg) 9 8.91 30.55 130.87 0.00 0.00 769.61
Lorazepam (mg/kg) 5 4.95 0.07 0.38 0.00 0.00 3.00
Hydromorphone (mg/kg) 2 1.98 0.02 0.20 0.00 0.00 2.00
Clonidine (mg/kg) 1 0.99 0.00 0.01 0.00 0.00 0.10
Dexmedetomidine (mg/kg) 0 0 0.00 0.00 0.00 0.00 0.00

N = 101. Abbreviations: SD = standard deviation; Min = minimum; Max = Maximum; mg = milligram; mcg = microgram; kg = kilogram