Table 3.
30-year absolute risk estimates of colorectal cancer for 50-year-old men and women
| Subgroup | Cases n(%)/Controls n(%) | 30 Year Risk, % (95% CI) | ||
|---|---|---|---|---|
| Men | Women | Men | Women | |
| No colonoscopy | ||||
| Low genetic risk | ||||
| Unfavourable lifestyle | 164(40)/88(26) | 40(15)/26(12) | 6.2 (5.4–7.1) | 4.9 (3.9–6.2) |
| Intermediate lifestyle | 157(38)/123(36) | 101 (38)/53(24) | 4.9 (4.3–5.6) | 3.6 (3.0–4.3) |
| Favourable lifestyle | 87(21)/134(39) | 123(47)/143(64) | 3.5 (3.0–4.0) | 2.5 (2.1–2.9) |
| Intermediate genetic risk | ||||
| Unfavourable lifestyle | 260(41)/97(30) | 76(21)/20(9) | 9.4 (8.3–10.7) | 7.1 (5.7–8.8) |
| Intermediate lifestyle | 216(34)/120(37) | 131(36)/78(35) | 7.4 (6.5–8.3) | 5.2 (4.4–6.1) |
| Favourable lifestyle | 153(24)/108(33) | 156(43)/126(56) | 5.3 (4.7–6.1) | 3.6 (3.1–4.2) |
| High genetic risk | ||||
| Unfavourable lifestyle | 341(40)/115(36) | 118(21)/27(13) | 13.4 (11.8–15.1) | 10.6 (8.6–13.1) |
| Intermediate lifestyle | 302(35)/105(33) | 199(35)/57(28) | 10.6 (9.4–11.9) | 7.8 (6.7–9.1) |
| Favourable lifestyle | 208(24)/99(31) | 248(44)/119(59) | 7.6 (6.7–8.7) | 5.5 (4.8–6.3) |
| Colonoscopy | ||||
| Low genetic risk | ||||
| Unfavourable lifestyle | 53(36)/80(23) | 7(9)/21(11) | 2.1 (1.9–2.6) | 1.9 (1.5–2.4) |
| Intermediate lifestyle | 59(40)/145(41) | 33(40)/65(34) | 1.7 (1.5–2.0) | 1.4 (1.1–1.7) |
| Favourable lifestyle | 35(24)/129(36) | 42(51)/107(55) | 1.2 (1.0–1.4) | 0.9 (0.8–1.1) |
| Intermediate genetic risk | ||||
| Unfavourable lifestyle | 75(34)/110(29) | 23(15)/26(12) | 3.3 (2.9–3.1) | 2.7 (2.2–3.4) |
| Intermediate lifestyle | 80(36)/126(34) | 60(28)/60(28) | 2.6 (2.3–3.0) | 1.9 (1.7–2.4) |
| Favourable lifestyle | 67(30)/138(37) | 88(57)/129(60) | 1.9 (1.6–2.1) | 1.4 (1.2–1.6) |
| High genetic risk | ||||
| Unfavourable lifestyle | 120(38)/100(29) | 44(21)/22(10) | 4.8 (4.2–5.5) | 4.2 (3.3–5.2) |
| Intermediate lifestyle | 117(36)/127(37) | 66(32)/70(32) | 3.8 (3.3–4.3) | 3.0 (2.6–3.6) |
| Favourable lifestyle | 90(28)7118(34) | 98(47)7127(58) | 2.6 (2.3–3.1) | 2.1 (1.8–2.4) |
Abbreviations: CI, confidence interval