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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2020 Mar 27;125(2):190–195.e2. doi: 10.1016/j.anai.2020.03.018

Table 4:

Multivariate-Adjusted IgG-Concentration Differences (mg/dL) According to Sex and Race Stratified by Selected Indication for Testing (Asian vs White Patients and Black vs White Patients) (β, 95% CI)

Allergy/Immunology Autoimmune Disease

Asian Black White Asian Black White
No. of Patients (N, %) 35 (2.6%) 18 (1.3%) 1317 (96.1%) 20 (4.0%) 36 (7.3%) 440 (88.7%)

IgG +375.1 (+207.3, +543.0)* +191.8 (−32.3, +415.9) Ref +508.3 (+206.0, +810.7)* +342.8 (+128.0, +557.6)* Ref
IgG1 +162.2 (+61.1, +263.3)* +163.3 (+25.5, +301.2)* Ref +324.9 (+121.3, +528.4)* +215.8 (+64.4, +367.1)* Ref
IgG2 +233.7 (+175.4, +292)* +57.2 (−19.2, +133.6) Ref +323.0 (+224.0, +422.0)* +55.0 (−13.1, +123) Ref
IgG3 +10.5 (−2.4, +23.5) +20.8 (+3.0, +38.6)* Ref +36.5 (+3.5, +69.5)* +25.2 (+0.5, +50.0)* Ref
IgG4 +201.7 (+155.0, +248.4)* +2.5 (−49.3, +54.2) Ref +280.4 (+202.4, +358.3)* +4.1 (−37.7, +46.0) Ref
GI Disorder Infection

Asian Black White Asian Black White

No. of Patients (N, %) 29 (3.7%) 60 (7.7%) 694 (88.6%) 36 (2.3%) 80 (5.1%) 1449 (92.6%)

IgG +136.8 (−49.6, +323.3) +445.2 (+313.4, +577.0)* Ref +222.0 (+62.2, +381.7)* +598.1 (+491.6, +704.6)* Ref
IgG1 +108.6 (−25.6, +242.8) +322.8 (+223.8, +421.9)* Ref +124.4 (+16.4, +232.4)* +475.9 (+394.1, +557.7)* Ref
IgG2 +130.8 (+67, +194.6)* +101.8 (+58.1, +145.5)* Ref +130.9 (+78.4, +183.5)* +65.0 (+28.6, +101.3)* Ref
IgG3 +15.2 (−13.2, +43.7) +16.5 (−3.3, +36.4) Ref +16.7 (−3.3, +36.7) +69.8 (+49.6, +90.0)* Ref
IgG4 +19.6 (+1.9, +37.3)* +14.9 (+2.1, +27.7)* Ref +10.8 (−4.2, +25.8) +15.4 (+5.0, +25.7)* Ref
*

p < 0.05

Adjusted for age and sex but data not presented