Table 2 -.
Body composition and muscle function characteristics
| Healthy (n=19) | COPD (n=23) | P value | |
|---|---|---|---|
| Body Composition | |||
| Lean mass (kg) | 50.3 (3.0) | 49.4 (2.4) | 0.80 |
| Lean mass extremities (kg) | 21.0 (1.4) | 20.0 (1.0) | 0.51 |
| Fat mass (kg) | 27.2 (2.5) | 32.7 (3.5) | 0.23 |
| Fat mass trunk (kg) | 15.3 (1.2) | 16.3 (1.9) | 0.38 |
| Fat mass index (kg/m2) | 9.7 (1.0) | 11.6 (1.2) | 0.28 |
| Fat-free mass (kg) | 52.7 (3.1) | 51.3 (2.2) | 0.68 |
| Fat-free mass index (kg/m2)2 | 18.4 (0.8) | 18.1 (0.6) | 0.75 |
| Appendicular skeletal muscle mass (kg) | 21.0 (1.5) | 20.0 (0.9) | 0.51 |
| Appendicular skeletal muscle index (kg/m2)3 | 7.3 (0.4) | 7.1 (0.3) | 0.51 |
| Android fat (%)4 | 37.4 (2.5) | 37.3 (2.5) | 0.98 |
| Gynoid fat (%)4 | 34.4 (2.5) | 36.0 (1.7) | 0.54 |
| Fat % android/gynoid (ratio) | 1.02 (0.04) | 1.04 (0.05) | 0.88 |
| Muscle function | |||
| Inspiratory muscle strength (cm H2O) | 101.1 (11.8) | 68.7 (5.3) | 0.006 |
| Expiratory muscle strength (cm H2O) | 106.1 (5.9) | 101.9 (5.5) | 0.71 |
| Maximal handgrip strength (N) | 273.3 (15.8) | 217.3 (11.9) | 0.004 |
| Maximal leg extension force (N) | 335.3 (28.0) | 234.8 (17.5) | 0.003 |
| Other | |||
| PASE (score) | 150.5 (22.7) | 109.4 (12.7) | 0.08 |
| Daily protein intake per kg fat-free mass | 1.04 (0.07) | 0.99 (0.12) | 0.76 |
Values are mean (SE). Statistics are by unpaired t-test.
2
Fat-free mass index = (lean mass + bone mineral content)/height2.
3
Appendicular skeletal muscle index = (lean mass legs + lean mass arms)/height2.
4
Android fat and gynoid fat correspond to central and peripheral fat distribution, respectively. COPD: chronic obstructive pulmonary disease. PASE: physical activity questionnaire for the elderly.