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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Cell Signal. 2020 Jun 15;73:109696. doi: 10.1016/j.cellsig.2020.109696

Table 2. Predicted translation products of SMN circRNAs.

All AUGs resulting in peptides of at least 10 amino acids are reported. The first column gives the circRNA name. Start and stop exons give the location of AUG start codon and UAG/UAA stop codons, respectively. Start position refers to the position of the first nucleotide of AUG within the start exon. Stop position refers to the position of the last nucleotide of UAG/UAA within the stop exon. Peptide length refers to the predicted size in amino acids of the translation product. The last column refers to whether the circRNA ORF contains portions of the primary in-frame SMN ORF. N/A: There is no predicted stop codon, resulting in rolling-circle translation. ∞: Due to rolling-circle translation, the predicted translation product is of indeterminate length.

circRNA Start exon Start Position Stop exon Stop position Peptide length In frame?
C3–4 3 18 3 77 19 No
3 116 3 172 18 No
3 191 3 172 111 No
4 2 3 172 107 No
4 8 3 172 105 No
4 29 3 172 98 No
4 93 3 77 45 No
4 124 N/A N/A Yes
C2B–3–4 2B 14 3 172 92 No
3 18 3 77 19 No
3 116 3 172 18 No
3 191 2B 10 57 No
4 2 2B 10 53 No
4 8 2B 10 51 No
4 29 2B 10 44 No
4 93 2B 20 26 No
4 124 N/A N/A Yes
C2A–2B–3–4 2A 5 2A 37 10 No
2A 47 2B 10 11 No
2B 14 3 172 92 No
3 18 3 77 19 No
3 116 3 172 18 No
3 191 2A 37 66 No
4 2 2A 37 62 No
4 8 2A 37 60 No
4 29 2A 37 53 No
4 93 2A 8 22 No
4 124 N/A N/A Yes
C5–6 5 17 6 4 27 No
5 63 6 41 24 No
6 64 N/A N/A α Yes
6 75 6 41 57 No
6 82 N/A N/A Yes
6 109 N/A N/A Yes
C6–7–8A 6 64 7 46 32 Yes
6 75 8A 26 38 No
6 82 7 46 26 Yes
6 109 7 46 17 Yes
8A 27 8A 68 13 No
8A 139 6 41 14 No
C6–7–8A–9 6 64 7 46 32 Yes
6 75 8A 26 38 No
6 82 7 46 26 Yes
6 109 7 46 17 Yes
8A 27 8A 68 13 No
8A 139 6 41 48 No
C6–7–8A–9trl 6 64 7 46 32 Yes
6 75 8A 26 38 No
6 82 7 46 26 Yes
6 109 7 46 17 Yes
8A 27 8A 68 13 No
8A 139 7 46 87 Yes
C6–7–8A–10 6 64 7 46 32 Yes
6 75 8A 26 38 No
6 82 7 46 26 Yes
6 109 7 46 17 Yes
8A 27 8A 68 13 No
8A 139 10 32 11 No
10 62 6 41 25 No
10 83 6 41 18 No
C6–6B–7–8A 6 64 6B 51 32 Yes
6 75 6B 20 18 No
6 82 6B 51 26 Yes
6 109 6B 51 17 Yes
6B 93 7 46 20 Yes
8A 27 8A 68 13 No
8A 139 6 41 48 No
C6–7–8A–9–10 6 64 7 46 32 Yes
6 75 8A 26 38 No
6 82 7 46 26 Yes
6 109 7 46 17 Yes
8A 27 8A 68 13 No
8A 139 10 32 45 No
10 62 6 41 25 No
10 83 6 41 18 No
C6–7–8A–9trl-10 6 64 7 46 32 Yes
6 75 8A 26 38 No
6 82 7 46 26 Yes
6 109 7 46 17 Yes
8A 27 8A 68 13 No
8A 139 10 45 48 No
10 62 6 41 25 No
10 83 6 41 18 No