Table 4 –
Multivariable logistic regression to predict locally advanced disease among men with clinical T2 prostate cancer (n = 287)
| Variable | Odds ratio | 95% Confidence interval | p value |
|---|---|---|---|
| Age at RP (increase per 5 yr) | 1.16 | 0.95, 1.41 | 0.14 |
| Preoperative PSA (ng/ml) a | NA | NA | 0.0009 |
| Clinical T stage | 0.038 | ||
| T2A | Reference | – | |
| T2B | 2.03 | 0.89, 4.63 | |
| T2C | 3.34 | 1.08, 9.98 | |
| Gleason grade group | <0.0001 | ||
| 1–2 | Reference | – | |
| 3 | 1.99 | 0.96, 4.12 | |
| 4 | 3.85 | 2.01, 7.37 | |
| BRCA1 | 1.72 | 0.76, 3.91 | 0.2 |
NA = not available; PSA = prostate-specific antigen; RP = radical prostatectomy.
a
Nonlinear terms (cubic splines) used.