Table 2.
Associations of maternal o,p’-DDT (ln ng/ml) with continuous measures of adiposity in middle-aged daughters of the CHDS cohort. Associations with waist circumference (cm) and body mass index (BMI, kg/m2) were estimated using a linear mixed model.
| Parameters | Waist circumference | BMI |
|---|---|---|
| N subjects | 511 | 508 |
| Exposure distribution | Continuous | Continuous |
| Outcome distribution | Continuous | Continuous |
| Beta (95% CI) estimate units | cm per ln ng/ml | kg/m2 per ln ng/ml |
| Model 11 | 1.17 (0.18, 2.15) | 0.57 (0.14, 1.01) |
| Model 22 | 1.25 (0.30, 2.20) | 0.61 (0.18, 1.04) |
| Model 33 | 1.19 (0.26, 2.13) | 0.59 (0.17, 1.00) |
Model 1 includes o,p’-DDT coded as 3 dummy variables representing quartiles 2, 3 and 4 vs. quartile 1 as the reference.
Model 2 includes o,p’-DDT coded as 3 dummy variables representing quartiles 2, 3 and 4 vs. quartile 1 as the reference and is adjusted for mothers of subjects’ characteristics: pre-pregnancy BMI (<25, 25–29, ≥30 kg/m2), education (<high school, ≥high school), foreign birthplace (yes, no); and, study subjects’ characteristic: menopause (none, any).
Model 3 includes o,p’-DDT coded as 3 dummy variables representing quartiles 2, 3 and 4 vs. quartile 1 as the reference and is adjusted for mothers of subjects’ characteristics: pre-pregnancy BMI (<25, 25–29, ≥30 kg/m2), education (<high school, ≥high school), foreign birthplace (yes, no); and, study subjects’ characteristics: menopause (none, any), exercise (continuous hours/week) and physician-diagnosed and medicated thyroid condition (yes, no).