The spectrum of imaging findings in individuals affected by changes in WDR45. A. Imaging from three individuals demonstrating low volume, including of the corpus callosum (* left panel) and supra- and infra-tentorial regions middle panel). B. In some individuals, iron deposition was absent in the initial set of images, but later was evident (second row). Evidence of iron deposition was found in a subset of individuals in the Substantia Nigra (SN) and/or Globus Pallidus (GP) using T2, GRE, and SWI modalities. C. In a subset of individuals, myelination was delayed (left and middle panels) and low in volume (right panel).