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. 2020 Jan 29;57(11):752–759. doi: 10.1136/jmedgenet-2019-106519

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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CA9 immunochemistry in patients tumours with a VHL E1' mutation showed a membranous immunostaining on a cluster of cells in patient #10 PPGL (A). PNMT and VHL (E1-E2 transcript) genes expression by RT-qPCR in patients #3 and #10 showed a low expression of the two genes in patient #10 tumours (B).