Table 1.

Main clinical and tumour characteristics of the different cohorts

Total patients n=1167
VHL-like, n=76 patients
Age at first diagnosis mean (min-max)	45.4 (20–76)
Multiple haemangioblastomas	16 (21%)
Haemangioblastoma with another VHL tumour	28 (37%)
One VHL tumour and family history of VHL tumour	32 (42%)
Multiple VHL tumours, n=70 patients
Age at first diagnosis mean, (min-max)	55 (11–81)
Three or more VHL tumours	3 (4%)
Two VHL tumours	67 (96%)
Single VHL tumour, n=75 patients
Age at first diagnosis mean (min-max)	34.6 (11–78)
Clear cell renal cell carcinoma	3 (4%)
Cerebral haemangioblastoma	27 (36%)
Retinal haemangioblastoma	10 (13.3%)
Other tumours	35 (46.6%)
PPGL, n=946 patients
Age at first diagnosis mean (min-max)	43 (8–94)
Benign PPGL	869 (92%)
Single benign PPGL	771 (82%)
Multiple benign PPGL	98 (10%)
Metastatic PPGL	77 (8%)
Single metastatic PPGL	67 (7%)
Multiple metastatic PPGL	10 (1%)
Familial PPGL	17 (2%)

PPGL, paraganglioma; VHL, von Hippel-Lindau.