Table 1:
Participant Number | Gender | Age | Weight (kg) | Height (cm) | Ethnicity | HCV Genotype | Mode of Acquiring HCV | HIV(Antiretro viral Therapy) | HCV Treatment Outcome* |
---|---|---|---|---|---|---|---|---|---|
2 | Female | 23 | 59.0 | 166 | Caucasian | 3a | IDU | No | SVR |
4 | Male | 47 | 76.0 | 180.5 | Caucasian | 1a | IDU | No | Relapse |
8 | Male | 31 | 61.1 | 170 | Asian | 1a | IDU | Yes (nevirapine, TDF, FTC) | Relapse |
9 | Male | 73 | 68.1 | 178 | Caucasian | 1a | SE, MSM | Yes (etravirine, lamivudine, raltegravir) | Relapse |
10 | Male | 39 | 64.0 | 171 | Caucasian | 1a | IDU | Yes (raltegravir, TDF, FTC) | Relapse |
12 | Male | 31 | 94.6 | 186 | Caucasian | 1a | SE, MSM | Yes (rilpivirine, TDF, FTC) | Relapse |
13 | Male | 44 | 68.0 | 179 | Asian | 1a | IDU | Yes (efarivirenz, TDF, FTC) | Relapse |
14 | Male | 49 | 77.3 | 185 | Caucasian | 1a | SE, MSM | Yes (TDF, FTC) | Relapse |
15 | Male | 54 | 91.1 | 181 | Caucasian | 1a | SE, MSM | Yes (efavirenz, TDF, FTC) | Relapse |
17 | Male | 53 | 94.3 | 171 | Hispanic | 3a | SE, MSM | Yes (rilpivirine, TDF, FTC) | Non-response‡ |
18 | Male | 30 | 79.4 | 190 | Caucasian | 1a | IDU | Yes (TDF, FTC) | Non-response |
19 | Male | 45 | 90.5 | 186 | Caucasian | 3a | IDU | No | Relapse |
Non-response, signifies that HCV RNA was quantifiable at end of treatment (EOT); Relapse, signifies quantifiable HCV RNA, confirmed as homologous virus, at post-treatment week 12 despite unquantifiable HCV RNA at EOT;
Spontaneous clearance of virus more than 12 weeks post treatment observed; IDU, injecting drug use; MSM, men who have sex with men. HIV, human immunodeficiency virus; SVR, sustained virological response; SE, sexual exposure; TDF, tenofovir disoproxil fumarate; FTC, emtricitabine.