Figure 3.

A) Secondary structure of peptide residues in the 150 kDa Aβ(1–42) oligomer, predicted by TALOS-N software, and the measured secondary ¹³C NMR backbone chemical shifts upon which the TALOS-N prediction is based. B) The NMR linewidths of CO (green), C^α (red), and C^β (blue) reported as full widths at half maximum measured by nonlinear regression of cross peaks in the 2D-fpRFDR ¹³C-¹³C NMR spectra to Gaussian functions.