Skip to main content
. Author manuscript; available in PMC: 2021 Jul 24.
Published in final edited form as: J Mol Biol. 2020 May 26;432(16):4388–4407. doi: 10.1016/j.jmb.2020.05.018

Table 1.

Isotopic labeling employed for the 150 kDa oligomer samples analyzed in this study.

Sample Isotopic Labeling
Uniform 13C-labeling and 15N- labeling at the indicated residues:
1 K16, F20, V24, G37
2 D7, G9, E11.L17, F19, A21
3 E11, F19, 131, V36
4 E11.L17.A21, M35, G38
5 I32, M35, G37, V40
6 Q15, V18, A21
7 S8, Y10, V12, L34, G38, 141
8 V12, E22, S26, N27, G33
9 V12, F20, D23, K28, G29
10 E11, H13, Q15, L17
11 E11, K16, F19, V36
12 A2, E3, F4, G9, V39
13 H14, K16, L34, A42
14 F19, V24, G25, A30, 131, L34, M35 [33]
Selective 13C-labeling at the indicated sites:
A L17 CO
B V18 CO
C F19 CO
D F20 CO
E A21 CO
F L17 CO and F19 CO
G V18COandA21 CO
H L17 CO and A21 CO
I V18 CO and A21 CO (50% isotope-diluted)