Study characteristics |
Methods |
Randomized, controlled |
Participants |
Elective on‐pump CABG only |
Interventions |
Amiodarone vs. Biatrial Pacing vs. Control |
Outcomes |
AF lasting at least 1 hour or associated with hemodynamic compromise; Mortality |
Follow‐Up |
ICU discharge |
Concurrent Antiarrhythmic Medications |
None |
Notes |
|
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Low risk |
Externally validated sequence generator |
Allocation concealment (selection bias) |
Low risk |
Allocation based on computer‐generated randomizer |
Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Insufficient information; Pacing, therefore unblinded |
Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
Single‐blinded, therefore physicians know treatment regimen |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No missing outcome data |
Selective reporting (reporting bias) |
Low risk |
All outcomes reported |
Intention‐to‐treat analysis |
Unclear risk |
Not reported |