| Study characteristics |
| Methods |
Double‐blind, randomized, placebo‐controlled |
| Participants |
Valve surgery (with or without CABG) |
| Interventions |
Amiodarone vs. placebo |
| Outcomes |
AF; Mortality; LOS; Cost |
| Follow‐Up |
14 days |
| Concurrent Antiarrhythmic Medications |
Beta‐blockers, Calcium channel blockers |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
Computer‐generated randomization software |
| Allocation concealment (selection bias) |
Unclear risk |
Insufficient information |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
Double‐blind |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Double‐blind |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No missing outcome data |
| Selective reporting (reporting bias) |
Low risk |
All outcomes reported |
| Intention‐to‐treat analysis |
High risk |
No |
