| Study characteristics |
| Methods |
Randomized, controlled |
| Participants |
On‐pump CABG only |
| Interventions |
Sotalol vs. Control |
| Outcomes |
SVA lasting at least 1 minute with a heart rate of greater than 120 bpm; LOS |
| Follow‐Up |
Hospital discharge; 1‐3 month postoperative follow‐up |
| Concurrent Antiarrhythmic Medications |
None |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
No randomization method mentioned |
| Allocation concealment (selection bias) |
Unclear risk |
Insufficient information |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
Not placebo controlled |
| Blinding of outcome assessment (detection bias)
All outcomes |
Unclear risk |
Insufficient information |
| Incomplete outcome data (attrition bias)
All outcomes |
High risk |
Event rates based on post‐randomization drop‐outs, but baseline characteristics not adjusted for |
| Selective reporting (reporting bias) |
High risk |
Adverse outcomes such as bradycardia not reported as risk factor, although high dropout rate due to complications |
| Intention‐to‐treat analysis |
High risk |
No |
