Table 1.

Patient Characteristics in Studies Included in the Meta-Analysis

Study	Age (years)	Patients desiring future fertility	Fibroid types (%)					No. of treated fibroids per patient	Total fibroid volume (cm3)	HRQLa	SSSa
			Submucous	Intramural	Subserous	Transmural	Unspecified
Bongers et al.15	43b	Excluded	61	30	0	9	0	1.8 ± 1.1	10 (<1, 77)c	34 ± 19	62 ± 17
Brölmann et al.16
Garza-Leal17	43b	Excluded	49	46	0	6	0	2.1	—d	27 ± 22	65 ± 17
Braun et al.18	40 ± 7	Included	4	35	49	5	7	4.2 ± 3.3	—d	—	—
Brucker et al.19	40 ± 8	Included	0	49	51	0	0	2.9 ± 2.6	—d	77	40
Hahn et al.20
Krämer et al.21
Carrafiello et al.22	40 (27, 51)e	Excluded	9	45	0	0	45	1 (1, 1)c	102 (45, 278)e	62 (37, 86)e	50 (32, 67)e
Cho et al.23	43 ± 4	Excluded	0	0	0	0	100	—	65 ± 13	59 ± 16	49 ± 11
Cho et al.24	40 ± 7	Included	100	0	0	0	0	—	112 ± 53	46 ± 13	76 ± 9
Chudnoff et al.25	43 ± 5	Excluded	21	46	25	5	2	5.0 ± 4.4	80 ± 84	39 ± 19	60 ± 19
Galen et al.26
Guido et al.27
Berman et al.28
Chudnoff et al.29	43 (31, 50)c	Excluded	21	49	10	21	0	3.0 ± 2.1	71 ± 85	40 ± 21	55 ± 19
Miller and Osman30
Galen et al.31	42 ± 6	Excluded	6	50	38	3	3	3 (1, 20)c	—	49 ± 24	54 ± 23
Garza-Leal et al.32
Robles et al.33
Ghezzi et al.34	42 (40, 50)c	Excluded	0	100	0	0	0	1 (1, 3)c	77 (15, 333)c	63 (23, 94)c	44 (13, 91)c
Bergamini et al.35
Iversen and Dueholm36	45 ± 7	Excluded	20	80	0	0	0	1 (1, 3)c	123 (24, 675)c	22 ± 21	61 ± 17
Iversen et al.37
Jiang et al.38	41 ± 6	Included	9	78	13	0	0	1 (1, 3)c	60 (7, 321)c	72 ± 13	32 ± 15
Kim et al.39	40 ± 7	Included	6	0	0	0	94	2 (1, 3)c	305 (48, 1022)e	—	57 ± 21
Lee et al.40	45 (42, 51)e	Excluded	100	0	0	0	0	1 (1, 1)c	58b	49 ± 15	71 ± 8
Marcos et al.41	44 ± 5	Included	0	71	29	0	0	1 (1, —)c	112 ± 65	—	—
Meng et al.42	39 ± 6	Excluded	13	66	21	0	0	1 (1, 3)c	70 ± 59	—	—
Rattray et al.43	39 ± 7	Included	0	0	0	0	100	3.4 ± 2.4	—d	40 ± 26	62 ± 20
Rey et al.44	39 ± 9	Included	100		0	0	0	—	122 ± 183	—	—
Turtulici et al.45	45 ± 8	Excluded	0	0	0	0	100	1.7 (1, 3)e	14 (5, 42)e	68 ± 36	—
Wu et al.46	41 (32, 52)c	Excluded	21	79	0	0	0	1.2 (1, 3)e	32 (1, 78)c	65 ± 41	45 ± 34

^aDerived from the UFS-QoL questionnaire.

^bEstimated.

^cMedian (min, max).

^dDiameter reported only.

^eMean (min, max).

HRQL, health-related quality of life; SSS, symptom severity score; UFS-QoL, Uterine Fibroid Symptom Health-Related Quality of Life Questionnaire.