Summary of findings 7. Walking versus lying.
Walking versus lying for reducing risk of maternal hypotension during spinal anaesthesia for caesarean section | |||||
Patient or population: women having spinal anaesthesia for caesarean section Setting: hospital setting in Australia Intervention: walking Comparison: lying | |||||
Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Quality of the evidence (GRADE) | |
Risk with lying | Risk with walking | ||||
Maternal hypotension requiring intervention | Study population | RR 0.71 (0.41 to 1.21) | 37 (1 RCT) | ⊕⊝⊝⊝ Very lowa,b | |
706 per 1000 | 501 per 1000 (289 to 854) | ||||
Maternal hypertension requiring intervention | No studies reported this outcome. | ||||
Maternal bradycardia requiring intervention | No studies reported this outcome. | ||||
Maternal nausea and/or vomiting | No studies reported this outcome. | ||||
Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 | No studies reported this outcome. | ||||
Neonal Apgar score < 8 at 5 minutes | No studies reported this outcome. | ||||
Admission to neonatal intensive care unit | No studies reported this outcome. | ||||
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: confidence interval; RR: risk ratio. | |||||
GRADE Working Group grades of evidence High quality: We are very confident that the true effect lies close to that of the estimate of the effect Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect |
aParticipants and anaesthetists not blinded in 1 study with 100% weight in analysis (−1). bWide CI that includes potential for benefit or no benefit from the intervention. Small sample size (−2).