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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Summary of findings 7. Walking versus lying.

Walking versus lying for reducing risk of maternal hypotension during spinal anaesthesia for caesarean section
Patient or population: women having spinal anaesthesia for caesarean section
Setting: hospital setting in Australia
Intervention: walking
Comparison: lying
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) № of participants
(studies) Quality of the evidence
(GRADE)
Risk with lying Risk with walking
Maternal hypotension requiring intervention Study population RR 0.71
(0.41 to 1.21) 37
(1 RCT) ⊕⊝⊝⊝
Very lowa,b
706 per 1000 501 per 1000
(289 to 854)
Maternal hypertension requiring intervention No studies reported this outcome.
Maternal bradycardia requiring intervention No studies reported this outcome.
Maternal nausea and/or vomiting No studies reported this outcome.
Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 No studies reported this outcome.
Neonal Apgar score < 8 at 5 minutes No studies reported this outcome.
Admission to neonatal intensive care unit No studies reported this outcome.
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; RR: risk ratio.
GRADE Working Group grades of evidenceHigh quality: We are very confident that the true effect lies close to that of the estimate of the effect
Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

aParticipants and anaesthetists not blinded in 1 study with 100% weight in analysis (−1).
bWide CI that includes potential for benefit or no benefit from the intervention. Small sample size (−2).