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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Comparison 3. Crystalloid: high vs low preload volume.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
3.1 Women with hypotension requiring intervention 3 192 Risk Ratio (M‐H, Random, 95% CI) 0.55 [0.29, 1.02]
3.1.1 15 mL/kg crystalloid 2 67 Risk Ratio (M‐H, Random, 95% CI) 0.56 [0.33, 0.96]
3.1.2 20 mL/kg crystalloid 2 125 Risk Ratio (M‐H, Random, 95% CI) 0.51 [0.11, 2.44]
3.2 Nausea and/or vomiting 1 80 Risk Ratio (M‐H, Random, 95% CI) 1.20 [0.40, 3.62]
3.3 Apgar < 8 at 5 min 1   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
3.3.1 15 mL/kg crystalloid 1 45 Risk Ratio (M‐H, Random, 95% CI) Not estimable
3.3.2 20 mL/kg crystalloid 1 45 Risk Ratio (M‐H, Random, 95% CI) Not estimable