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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Comparison 12. Ephedrine vs control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
12.1 Women with hypotension requiring intervention 22 1401 Risk Ratio (M‐H, Random, 95% CI) 0.65 [0.53, 0.80]
12.2 Women with hypertension requiring intervention 7 520 Risk Ratio (M‐H, Random, 95% CI) 1.61 [1.00, 2.61]
12.3 Women with cardiac arrhythmia 3   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
12.3.1 Tachycardia 2 93 Risk Ratio (M‐H, Random, 95% CI) 1.12 [0.74, 1.70]
12.3.2 Bradycardia 2 103 Risk Ratio (M‐H, Random, 95% CI) 14.46 [0.87, 241.09]
12.4 Women with nausea and/or vomiting 13   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
12.4.1 Nausea and/or vomiting 5 219 Risk Ratio (M‐H, Random, 95% CI) 0.71 [0.22, 2.34]
12.4.2 Nausea 8 620 Risk Ratio (M‐H, Random, 95% CI) 0.68 [0.48, 0.96]
12.4.3 Vomiting 6 516 Risk Ratio (M‐H, Random, 95% CI) 0.68 [0.44, 1.07]
12.5 Neonates with acidosis (pH < 7.2) 9 576 Risk Ratio (M‐H, Random, 95% CI) 1.29 [0.67, 2.49]
12.6 Neonates: Apgar score 14   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
12.6.1 Apgar < 8 at 5 min 10 579 Risk Ratio (M‐H, Random, 95% CI) Not estimable
12.6.2 Apgar < 7 at 5 min 4 263 Risk Ratio (M‐H, Random, 95% CI) 1.14 [0.34, 3.81]