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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Comparison 16. Ephedrine vs phenylephrine.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
16.1 Women with hypotension requiring intervention 8 401 Risk Ratio (M‐H, Random, 95% CI) 0.92 [0.71, 1.18]
16.2 Women with hypertension requiring intervention 2 118 Risk Ratio (M‐H, Random, 95% CI) 1.72 [0.71, 4.16]
16.3 Cardiac dysrhythmia 5   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
16.3.1 Bradycardia 5 304 Risk Ratio (M‐H, Random, 95% CI) 0.37 [0.21, 0.64]
16.3.2 Tachycardia 1 57 Risk Ratio (M‐H, Random, 95% CI) 2.22 [0.44, 11.18]
16.4 Women with nausea and/or vomiting 4 204 Risk Ratio (M‐H, Random, 95% CI) 0.76 [0.39, 1.49]
16.5 Neonates with acidosis (pH < 7.2) 3 175 Risk Ratio (M‐H, Random, 95% CI) 0.89 [0.07, 12.00]
16.6 Neonates with Apgar score < 8 at 5 min 6 321 Risk Ratio (M‐H, Random, 95% CI) Not estimable