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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Comparison 31. Ondansetron vs control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
31.1 Women with hypotension requiring intervention 8 740 Risk Ratio (M‐H, Random, 95% CI) 0.67 [0.54, 0.83]
31.1.1 2 mg vs control 2 79 Risk Ratio (M‐H, Random, 95% CI) 0.90 [0.51, 1.58]
31.1.2 4 mg vs control 5 277 Risk Ratio (M‐H, Random, 95% CI) 0.46 [0.34, 0.63]
31.1.3 6 mg vs control 1 38 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.22, 1.03]
31.1.4 8 mg vs control 5 346 Risk Ratio (M‐H, Random, 95% CI) 0.85 [0.70, 1.03]
31.2 Women with bradycardia 8 740 Risk Ratio (M‐H, Random, 95% CI) 0.49 [0.28, 0.87]
31.2.1 2 mg vs control 2 79 Risk Ratio (M‐H, Random, 95% CI) 0.23 [0.02, 3.29]
31.2.2 4 mg vs control 5 277 Risk Ratio (M‐H, Random, 95% CI) 0.33 [0.16, 0.71]
31.2.3 6 mg vs control 1 38 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.2.4 8 mg vs control 5 346 Risk Ratio (M‐H, Random, 95% CI) 0.94 [0.38, 2.37]
31.3 Women with nausea or vomiting 7 653 Risk Ratio (M‐H, Random, 95% CI) 0.35 [0.24, 0.51]
31.3.1 2 mg vs control 2 79 Risk Ratio (M‐H, Random, 95% CI) 0.54 [0.18, 1.59]
31.3.2 4 mg vs control 5 277 Risk Ratio (M‐H, Random, 95% CI) 0.32 [0.17, 0.60]
31.3.3 6 mg vs control 1 38 Risk Ratio (M‐H, Random, 95% CI) 0.09 [0.01, 0.74]
31.3.4 8 mg vs control 4 259 Risk Ratio (M‐H, Random, 95% CI) 0.38 [0.19, 0.76]
31.4 Women with anaphylaxis 1 150 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.4.1 2 mg vs control 1 37 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.4.2 4 mg vs control 1 37 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.4.3 6 mg vs control 1 38 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.4.4 8 mg vs control 1 38 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.5 Neonatal Apgar score < 8 at 5 min 3 284 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.5.1 2 mg vs control 1 37 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.5.2 4 mg vs control 2 102 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.5.3 6 mg vs control 1 38 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.5.4 8 mg vs control 2 107 Risk Ratio (M‐H, Random, 95% CI) Not estimable
31.6 Neonatal pH < 7.2 2 134 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.05, 5.09]
31.6.1 4 mg vs control 1 65 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.05, 5.09]
31.6.2 8 mg vs control 1 69 Risk Ratio (M‐H, Random, 95% CI) Not estimable