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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Comparison 34. Ketamine vs saline.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
34.1 Women with hypotension requiring intervention 1 105 Risk Ratio (M‐H, Random, 95% CI) 0.79 [0.62, 1.01]
34.1.1 0.25 mg/kg IV ketamine 1 52 Risk Ratio (M‐H, Random, 95% CI) 0.83 [0.61, 1.14]
34.1.2 0.5 mg/kg IV ketamine 1 53 Risk Ratio (M‐H, Random, 95% CI) 0.73 [0.50, 1.07]
34.2 Women with nausea and/or vomiting 1 105 Risk Ratio (M‐H, Random, 95% CI) 0.79 [0.50, 1.25]
34.2.1 0.25 mg/kg IV ketamine 1 52 Risk Ratio (M‐H, Random, 95% CI) 0.91 [0.48, 1.71]
34.2.2 0.5 mg/kg IV ketamine 1 53 Risk Ratio (M‐H, Random, 95% CI) 0.69 [0.36, 1.31]
34.3 Apgar score < 8 at 5 min 1 105 Risk Ratio (M‐H, Random, 95% CI) Not estimable
34.3.1 0.25 mg/kg IV ketamine 1 52 Risk Ratio (M‐H, Random, 95% CI) Not estimable
34.3.2 0.5 mg/kg IV ketamine 1 53 Risk Ratio (M‐H, Random, 95% CI) Not estimable