Farid 2016.
Study characteristics | ||
Methods | RCT | |
Participants | 74 women Inclusion criteria: healthy patients; elective CS Exclusion criteria: patients who experienced complications during the surgery Setting: Pakistan |
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Interventions |
Crystalloid preload versus crystalloid coload Group 1 (P): received crystalloid preload 15 mL/kg Hartmann's solution 20 min prior to spinal anaesthesia Group 2 (C): received crystalloid coload 15 mL/kg Hartmann's solution at time of administration of spinal anaesthesia All women received standardised monitoring, standardised cannulation, standardised spinal anaesthetic technique and dose Hypotension was treated with vasopressor (phenylephrine or ephedrine) |
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Outcomes | Maternal: incidence of hypotension | |
Notes | Hypotension was defined as reduction in MAP by > 20% from baseline | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | "Randomly assigned by trainee anaesthesia or anaesthetist in charge of case" |
Allocation concealment (selection bias) | Unclear risk | Not reported |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not reported |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not reported |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | "Patients going into complications during surgery were excluded" – unspecified how many patients (if any) this involved. No further details provided |
Selective reporting (reporting bias) | Low risk | Not evident |
Other bias | Low risk | Not evident |