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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Farid 2016.

Study characteristics
Methods RCT
Participants 74 women
Inclusion criteria: healthy patients; elective CS
Exclusion criteria: patients who experienced complications during the surgery
Setting: Pakistan
Interventions Crystalloid preload versus crystalloid coload
Group 1 (P): received crystalloid preload 15 mL/kg Hartmann's solution 20 min prior to spinal anaesthesia
Group 2 (C): received crystalloid coload 15 mL/kg Hartmann's solution at time of administration of spinal anaesthesia
All women received standardised monitoring, standardised cannulation, standardised spinal anaesthetic technique and dose
Hypotension was treated with vasopressor (phenylephrine or ephedrine)
Outcomes Maternal: incidence of hypotension
Notes Hypotension was defined as reduction in MAP by > 20% from baseline
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "Randomly assigned by trainee anaesthesia or anaesthetist in charge of case"
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Not reported
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not reported
Incomplete outcome data (attrition bias)
All outcomes Unclear risk "Patients going into complications during surgery were excluded" – unspecified how many patients (if any) this involved. No further details provided
Selective reporting (reporting bias) Low risk Not evident
Other bias Low risk Not evident