Lin 1999.
Study characteristics | ||
Methods | RCT | |
Participants | 60 women Inclusion criteria: healthy parturients undergoing primary or repeat CS, gestation 33‐41 weeks, uncomplicated singleton, not in labour, ASA I |
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Interventions |
Colloid preload versus crystalloid preload Group 1: 500 mL dextran 40 (n = 30) Group 2: 1000 mL Ringer's lactate (n = 30) Study drug administered over 20 min prior to spinal All women received a standardised spinal anaesthetic technique with variable dose (1.8‐2.2mL 0.5% bupivacaine). |
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Outcomes |
Maternal: hypotension; uterine incision‐delivery time; estimated blood loss; urine output; nausea Neonatal: Apgar scores at 1 min and 5 min |
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Notes | Hypotension defined as SBP < 70% baseline | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method not described |
Allocation concealment (selection bias) | Unclear risk | Method not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Blinding not mentioned |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Blinding not mentioned |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Losses to follow‐up: not stated |
Selective reporting (reporting bias) | Unclear risk | Not reported |
Other bias | Unclear risk | Not apparent |