Skip to main content
. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Selvan 2004.

Study characteristics
Methods RCT
Participants 60 women
Inclusion criteria: healthy women awaiting elective caesarean under spinal anaesthesia
Interventions Colloid vs crystalloid preload
Group 1: HES 6% w/v 500 mL
Group 2: HES 6% w/v 1000 mL
Group 3: Hartmann's solution 1500 mL
All women were placed in the left lateral position and fluid was then preloaded over 15 min.
All women received a standardised anaesthetic technique and dose.
Outcomes Maternal: hypotension; heart rate; BP; ephedrine use
Neonatal: cord gases
Notes Hypotension defined as 20% reduction in SBP
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method not described
Allocation concealment (selection bias) Unclear risk Method not described
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk "Double blind" – no further details
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk "Double blind" – no further details
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Losses to follow‐up not stated
Selective reporting (reporting bias) Unclear risk Not apparent, but not well reported
Other bias Unclear risk Not apparent, but not well reported