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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Stein 1997.

Study characteristics
Methods RCT
Participants 75 women
Inclusion criteria: healthy women (55 of whom had experienced at least 1 previous birth) undergoing elective CS during spinal anaesthesia
Exclusion criteria: history of nausea and vomiting associated with previous surgery or anaesthesia; nausea or vomiting within 24 h prior to caesarean, history of diabetes mellitus, or morbid obesity
Interventions Acupressure versus metoclopramide versus placebo
Group 1: acupressure bands + 2 mL IV saline
Group 2: placebo wrist bands + 10 mg metoclopramide
Group 3: placebo wrist bands + 2 mL IV saline
Acupressure defined as pressure on the Neiguan (P6) acupuncture points of the wrist.
All women received a standardised preload of 1500‐2000 mL Ringer's lactate in addition to a standardised spinal anaesthetic technique and dose.
Outcomes Maternal: hypotension; nausea (score > 2); vomiting; anxiety
Neonatal: Apgar score < 7 at 5 min
Notes Hypotension was defined as a decrease in SBP more than 20% from baseline or < 100 mmHg.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method not described
Allocation concealment (selection bias) Unclear risk "Envelope system" – no further details
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Blinding: wrist bands were placed bilaterally by an anaesthetist not directly involved in the women's care. The acupressure bands were lightly covered with gauze and tapes so they could not be distinguished from the placebo bands.
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk As above
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Losses to follow‐up: not stated
Selective reporting (reporting bias) Low risk Not apparent
Other bias Low risk Not apparent