Stein 1997.
Study characteristics | ||
Methods | RCT | |
Participants | 75 women Inclusion criteria: healthy women (55 of whom had experienced at least 1 previous birth) undergoing elective CS during spinal anaesthesia Exclusion criteria: history of nausea and vomiting associated with previous surgery or anaesthesia; nausea or vomiting within 24 h prior to caesarean, history of diabetes mellitus, or morbid obesity |
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Interventions |
Acupressure versus metoclopramide versus placebo Group 1: acupressure bands + 2 mL IV saline Group 2: placebo wrist bands + 10 mg metoclopramide Group 3: placebo wrist bands + 2 mL IV saline Acupressure defined as pressure on the Neiguan (P6) acupuncture points of the wrist. All women received a standardised preload of 1500‐2000 mL Ringer's lactate in addition to a standardised spinal anaesthetic technique and dose. |
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Outcomes |
Maternal: hypotension; nausea (score > 2); vomiting; anxiety Neonatal: Apgar score < 7 at 5 min |
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Notes | Hypotension was defined as a decrease in SBP more than 20% from baseline or < 100 mmHg. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method not described |
Allocation concealment (selection bias) | Unclear risk | "Envelope system" – no further details |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Blinding: wrist bands were placed bilaterally by an anaesthetist not directly involved in the women's care. The acupressure bands were lightly covered with gauze and tapes so they could not be distinguished from the placebo bands. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | As above |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Losses to follow‐up: not stated |
Selective reporting (reporting bias) | Low risk | Not apparent |
Other bias | Low risk | Not apparent |