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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Ueyama 1992.

Study characteristics
Methods RCT
Participants 100 women (60 non‐labouring women scheduled for elective caesarean and 40 labouring women for emergency caesarean)
Exclusion criteria: women with placenta praevia, abruptio placenta; toxaemia
Interventions Ephedrine (various doses) versus control
Group1: ephedrine 5 mg
Group 2: ephedrine 10 mg
Group 3: no ephedrine
Ephedrine was administered with the spinal.
All women received a standardised preload of 1000 mL Ringer's lactate, a standardised spinal anaesthetic technique and dose.
Outcomes Maternal: hypotension; SAP
Notes Hypotension was defined as SAP lower than 80 mmHg
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Methods not described
Allocation concealment (selection bias) Unclear risk Methods not describe
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Blinding not stated
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Blinding not stated
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Losses to follow‐up: not stated
Selective reporting (reporting bias) Unclear risk Unclear reporting
Other bias Unclear risk Unclear reporting