Wilson 1998.
Study characteristics | ||
Methods | RCT | |
Participants | 70 women Inclusion criteria: pregnant women (ASA I or II) undergoing elective CS |
|
Interventions |
Glucose versus crystalloid preload Group 1: glucose 5% IV Group 2: normal saline IV Administered at 125 mL/h prior to spinal anaesthesia Unclear whether all women received the same anaesthetic technique and dose |
|
Outcomes |
Maternal: hypotension; total study solution received; total IV preload; glucose levels Neonatal: Apgar scores; umbilical cord gases |
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Notes | Hypotension was defined as SBP > 20% decrease | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Method not described |
Allocation concealment (selection bias) | Unclear risk | Method not described |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Blinding: study solutions "were enclosed in an opaque bag to maintain blinding"; "double‐blind" |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | As above |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Losses to follow‐up: not stated |
Selective reporting (reporting bias) | Unclear risk | Unclear reporting |
Other bias | High risk | Variable dose of local anaesthetic used for spinal anaesthesia |