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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Wilson 1998.

Study characteristics
Methods RCT
Participants 70 women
Inclusion criteria: pregnant women (ASA I or II) undergoing elective CS
Interventions Glucose versus crystalloid preload
Group 1: glucose 5% IV
Group 2: normal saline IV
Administered at 125 mL/h prior to spinal anaesthesia
Unclear whether all women received the same anaesthetic technique and dose
Outcomes Maternal: hypotension; total study solution received; total IV preload; glucose levels
Neonatal: Apgar scores; umbilical cord gases
Notes Hypotension was defined as SBP > 20% decrease
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Method not described
Allocation concealment (selection bias) Unclear risk Method not described
Blinding of participants and personnel (performance bias)
All outcomes Low risk Blinding: study solutions "were enclosed in an opaque bag to maintain blinding"; "double‐blind"
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk As above
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Losses to follow‐up: not stated
Selective reporting (reporting bias) Unclear risk Unclear reporting
Other bias High risk Variable dose of local anaesthetic used for spinal anaesthesia