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. 2020 Jul 1;2020(7):CD002251. doi: 10.1002/14651858.CD002251.pub4

Yokoyama 1997.

Study characteristics
Methods RCT
Participants 30 women
Inclusion criteria: healthy women undergoing elective CS under spinal anaesthesia at term
Setting: Japan
Interventions Dopamine versus control
Group 1: dopamine continuous infusion 5 µg/kg/min
Group 2: non‐dopamine infusion
All women received a preload of 1000 mL of Ringer's lactate
All women received a variable anaesthetic technique (L2‐3 or L3‐4) with variable 0.3% dibucaine doses (1.6‐2.0 mL)
Outcomes Maternal: hypotension; BP; heart rate
Neonatal: Apgar scores
Notes Hypotension was defined as 90% or less of baseline BP
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Not reported
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not reported
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Not reported
Selective reporting (reporting bias) Unclear risk Not apparent, but not well reported
Other bias Unclear risk Not apparent, but not well reported