Boswell 2008.

Methods	RCT
Participants	105 women undergoing elective caesarean section
Interventions	Group 1: received a 1‐mg/min ephedrine infusion from the time of injection of the spinal solution until uterine incision Group 2: received a 9‐mg ephedrine bolus at the time of injection of the spinal solution. Group 3: received no prophylactic ephedrine
Outcomes	Maternal: time of hypotension; volume of rescue fluid; dose of rescue ephedrine Neonatal: Apgar scores
Notes	If SBP fell below IBP, a 250‐mL rescue bolus of normal saline and ephedrine 6 mg were given. If, after 2 min the SBP was still < IBP, a further 6‐mg bolus of ephedrine was given. If, after a further 2 min, the SBP remained < IBP, another 250‐mL bolus of saline with ephedrine 6 mg was given. This 4‐min cycle would be repeated until the SBP was > IBP. The study continued until uterine incision. Abstract only. Unclear whether intervention is for treatment or prevention of hypotension – first author's institution contacted 26 June 2017, awaiting response