2. Critical review form; randomised studies.

yes ‐ no

Did study population meet our criteria? or: is it possible to analyse patients that meet our criteria separately? Was assignment of patients to treatment randomised? Were patients analysed in the groups to which they were randomised? Were the groups similar at the start of the trial? Aside from the experimental intervention, were the groups treated equally? Were all patients who entered the trial accounted for at its conclusion? How long was follow up? (Median and range) Were interventions defined adequately? Were all clinically important outcomes considered? ‐disease free survival ‐complications