| 1.1 All‐cause death |
6 |
1517 |
Risk Ratio (M‐H, Random, 95% CI) |
0.90 [0.61, 1.32] |
| 1.1.1 Cerebrolysin dose: 30 mL for 10 days |
3 |
1235 |
Risk Ratio (M‐H, Random, 95% CI) |
0.88 [0.56, 1.39] |
| 1.1.2 Cerebrolysin dose: 50 mL for 21 days |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
0.87 [0.29, 2.58] |
| 1.1.3 Cerebrolysin dose: 10 mL and 50 mL for 10 days |
1 |
36 |
Risk Ratio (M‐H, Random, 95% CI) |
1.17 [0.37, 3.73] |
| 1.1.4 Cerebrolysin dose: 30 mL for 7 days then 10 mL 5 days a week for 3 weeks |
1 |
100 |
Risk Ratio (M‐H, Random, 95% CI) |
0.50 [0.05, 5.34] |
| 1.2 Total number of people with SAEs |
4 |
1435 |
Risk Ratio (M‐H, Random, 95% CI) |
1.15 [0.81, 1.65] |
| 1.2.1 Cerebrolysin dose: 30 mL for 10 days |
2 |
1189 |
Risk Ratio (M‐H, Random, 95% CI) |
1.23 [0.84, 1.81] |
| 1.2.2 Cerebrolysin dose: 50 mL for 21 days |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
0.75 [0.26, 2.12] |
| 1.2.3 Cerebrolysin dose: 30 mL for 7 days then 10 mL 5 days a week for 3 weeks |
1 |
100 |
Risk Ratio (M‐H, Random, 95% CI) |
1.00 [0.15, 6.82] |
| 1.3 Total number of people with fatal SAEs |
3 |
1335 |
Risk Ratio (M‐H, Random, 95% CI) |
0.90 [0.59, 1.38] |
| 1.3.1 Cerebrolysin dose: 30 mL for 10 days |
2 |
1189 |
Risk Ratio (M‐H, Random, 95% CI) |
0.90 [0.57, 1.44] |
| 1.3.2 Cerebrolysin dose: 50 mL for 21 days |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
0.87 [0.29, 2.58] |
| 1.4 Total number of people with non‐fatal SAEs |
4 |
1435 |
Risk Ratio (M‐H, Random, 95% CI) |
2.15 [1.01, 4.55] |
| 1.4.1 Cerebrolysin dose: 30 mL for 10 days |
2 |
1189 |
Risk Ratio (M‐H, Random, 95% CI) |
2.86 [1.23, 6.66] |
| 1.4.2 Cerebrolysin dose: 50 mL for 21 days |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
0.29 [0.01, 7.03] |
| 1.4.3 Cerebrolysin dose: 30 mL for 7 days then 10 mL 5 days a week for 3 weeks |
1 |
100 |
Risk Ratio (M‐H, Random, 95% CI) |
1.00 [0.15, 6.82] |
| 1.5 Total number of people with adverse events |
4 |
1435 |
Risk Ratio (M‐H, Random, 95% CI) |
0.97 [0.85, 1.10] |
| 1.5.1 Cerebrolysin dose: 30 mL for 10 days |
2 |
1189 |
Risk Ratio (M‐H, Random, 95% CI) |
0.96 [0.83, 1.11] |
| 1.5.2 Cerebrolysin dose 50 mL for 21 days |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
1.62 [0.69, 3.82] |
| 1.5.3 Cerebrolysin dose: 30 mL for 7 days then 10 mL 5 days a week for 3 weeks |
1 |
100 |
Risk Ratio (M‐H, Random, 95% CI) |
0.86 [0.44, 1.66] |
| 1.6 Non‐death attrition |
6 |
1517 |
Risk Ratio (M‐H, Random, 95% CI) |
0.97 [0.45, 2.06] |
| 1.6.1 Cerebrolysin dose: 30 mL for 10 days |
3 |
1235 |
Risk Ratio (M‐H, Random, 95% CI) |
0.87 [0.50, 1.52] |
| 1.6.2 Cerebrolysin dose: 50 mL for 21 days |
1 |
146 |
Risk Ratio (M‐H, Random, 95% CI) |
0.26 [0.08, 0.91] |
| 1.6.3 Cerebrolysin dose: 10 mL and 50 mL for 10 days |
1 |
36 |
Risk Ratio (M‐H, Random, 95% CI) |
Not estimable |
| 1.6.4 Cerebrolysin dose: 30 mL for 7 days then 10 mL 5 days a week for 3 weeks |
1 |
100 |
Risk Ratio (M‐H, Random, 95% CI) |
2.67 [1.14, 6.25] |
