Comparison 1. Ketogenic diet versus usual care.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Seizure freedom: children	4	385	Risk Ratio (M‐H, Fixed, 95% CI)	3.16 [1.20, 8.35]
1.2 Seizure freedom: adults	2	141	Risk Ratio (M‐H, Fixed, 95% CI)	Not estimable
1.3 50% or greater reduction in seizure frequency: children	4	385	Risk Ratio (M‐H, Fixed, 95% CI)	5.80 [3.48, 9.65]
1.4 50% or greater reduction in seizure frequency: adults	2	141	Risk Ratio (M‐H, Random, 95% CI)	5.03 [0.26, 97.68]
1.5 Treatment withdrawal: children	5	425	Risk Ratio (M‐H, Fixed, 95% CI)	1.08 [0.74, 1.57]
1.6 Treatment withdrawal: adults	2	141	Risk Ratio (M‐H, Random, 95% CI)	5.38 [0.42, 69.53]