Table 1.
Similarities and Difference between COVID19 and tuberculosis (TB).
| COVID 19 | Tuberculosis | |
|---|---|---|
| Differences | ||
| Onset | Acute | Chronic |
| Transmission | droplet-transmitted, by touching | airborne transmission; by inhalation |
| Pathogen | Viral disease SARS COV2 |
Bacterial disease Mycobacterium tuberculosis |
| Incubation period (exposure to disease) | Short (5-14 days) | Longer |
| Clinical feature |
|
|
| Testing specimen | nasopharyngeal or oropharyngeal swab | Sputum |
| Diagnostic tests | RT-PCR; rapid test antibody kit, Chest CT scan | Chest radiograph, Mycobacterium culture or molecular techniques, demonstration of acid-fast bacilli (AFB), serological assays |
| Pathology | Endothelial damage and coagulopathy small vessels | Caseation necrosis and granuloma formation |
| Treatment | Supportive; HCQS? antiviral Remdesivir | anti-tuberculosis treatment |
| National policy adoption | Fast | Slow |
| Prevention |
Current: Self- distancing, hand washing, PPE strategy Future: Vaccine Bacilli Calmette-Guerin (BCG) vaccination? Role yet to be proved |
Bacille Calmette-Guérin (BCG) vaccination |
| Similarities | ||
| Organ affected | Lung | Lung |
| Genetic and non-genetic factors-lack of knowledge for individual susceptibility | Yes | Yes |
| Spread | Close contact | Close contact |
| Rapid diagnosis | Required | Required |
| Action strategy | Find, Track, Trace, Test, Isolate and Prevent strategy | Find Test, Treat, Monitor and Prevent strategy. DOTS and Monitoring of treatment |
| Health system | Burden | Burden |
| Public awareness | Required | Required |
| Data sharing platform at national and international level | lacking | lacking |
| Mortality | High | High |
| Risk factors | Elderly, Diabetes, HIV immunosuppression, chronic obstructive pulmonary disease | Elderly, Diabetes, HIV immunosuppression, chronic obstructive pulmonary disease |
| Personal protection measures | basic infection prevention and control, cough etiquette, patient triage, hand washing | basic infection prevention and control, cough etiquette, patient triage |
| Role of digital health technologies | Yes | Yes |
Abbreviations: RT- PCR-Real Time Polymerase Chain Reaction; HIV- Human Immunodeficiency Virus; HCQS-hydroxychloroquine sulphate.