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. 2020 Jul 29;14(5):1439–1443. doi: 10.1016/j.dsx.2020.07.034

Table 1.

Similarities and Difference between COVID19 and tuberculosis (TB).

COVID 19 Tuberculosis
Differences
Onset Acute Chronic
Transmission droplet-transmitted, by touching airborne transmission; by inhalation
Pathogen Viral disease
SARS COV2
Bacterial disease
Mycobacterium tuberculosis
Incubation period (exposure to disease) Short (5-14 days) Longer
Clinical feature
  • Coughing more commonly a dry at presentation

  • fever and cough: rapid onset

  • shortness of breath: early

  • Coughing in TB is usually productive of sputum and even blood

  • fever and cough: much longer period

  • shortness of breath: later stage or as a long-term sequel

Testing specimen nasopharyngeal or oropharyngeal swab Sputum
Diagnostic tests RT-PCR; rapid test antibody kit, Chest CT scan Chest radiograph, Mycobacterium culture or molecular techniques, demonstration of acid-fast bacilli (AFB), serological assays
Pathology Endothelial damage and coagulopathy small vessels Caseation necrosis and granuloma formation
Treatment Supportive; HCQS? antiviral Remdesivir anti-tuberculosis treatment
National policy adoption Fast Slow
Prevention Current: Self- distancing, hand washing, PPE strategy
Future: Vaccine
Bacilli Calmette-Guerin (BCG) vaccination?
Role yet to be proved
Bacille Calmette-Guérin (BCG) vaccination
Similarities
Organ affected Lung Lung
Genetic and non-genetic factors-lack of knowledge for individual susceptibility Yes Yes
Spread Close contact Close contact
Rapid diagnosis Required Required
Action strategy Find, Track, Trace, Test, Isolate and Prevent strategy Find Test, Treat, Monitor and Prevent strategy. DOTS and Monitoring of treatment
Health system Burden Burden
Public awareness Required Required
Data sharing platform at national and international level lacking lacking
Mortality High High
Risk factors Elderly, Diabetes, HIV immunosuppression, chronic obstructive pulmonary disease Elderly, Diabetes, HIV immunosuppression, chronic obstructive pulmonary disease
Personal protection measures basic infection prevention and control, cough etiquette, patient triage, hand washing basic infection prevention and control, cough etiquette, patient triage
Role of digital health technologies Yes Yes

Abbreviations: RT- PCR-Real Time Polymerase Chain Reaction; HIV- Human Immunodeficiency Virus; HCQS-hydroxychloroquine sulphate.