Fig. 3. Event-free survival (EFS) and overall survival (OS) according to MRD status in peripheral blood.
a EFS from MRD landmark (final response assessment/MRD evaluation). b OS from MRD landmark (final response assessment/MRD evaluation). MRD minimal residual disease. For this calculation, the MRD status at the final restaging was considered. MRD negative < 10−4; positive ≥ 10−4 detected CLL cells per leukocytes, according to MRD-flow cytometry. For MRD-results from bone marrow please refer to Supplementary Figs. 1 and 2.