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DNMT3A mutation rate in bone marrow of healthy individuals vs. mice xenografts.
| Individual A | Mice xenografts (8 months after transplantation) | |||
|---|---|---|---|---|
| Mouse A1 | Mouse A2 | Mouse A3 | ||
| DNMT3Amut (S837X) | ||||
| VAF (%) | 23.1 | 23.8 | 10.8 | 30.8 |
| Individual B | Mice xenografts (8 months after transplantation) | |||
|---|---|---|---|---|
| Mouse B1 | Mouse B2 | Mouse B3 | ||
| DNMT3Amut (D768H) | ||||
| VAF (%) | 6.3 | 6.2 | 0 | 0 |
VAF variant allele frequency.
