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. 2020 Jul 28;10:12562. doi: 10.1038/s41598-020-69548-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Apoptotic exosome-like vesicles modulate gene expression of endothelial cells. (A) Heatmap of the 139 differentially expressed genes between the control and the apoptotic exosome-like vesicles-treated groups. Apoptotic exosome-like vesicles treatment increased the expression of 92 genes and a decrease of 47 genes. (B) Pie chart representation of the distribution of differentially expressed genes expressed as the percentage of each transcript biotype. (C) Gene ontology analysis of biological processes of differentially expressed antisense and protein-coding genes. (D) Characterization of differentially expressed genes according to endothelial functions. n = 2 for each condition.